In the middle ages, Nuremberg cemeteries, as was usual at that time, were located around the major churches within the city walls. Due to several waves of the plague, hygienic conditions in these cemeteries had become unacceptable. This is why on 1 October 1518, a decree by Emperor Maximilian I stipulated that people could only be buried outside the town walls. While the Sebald part of the town could resort to the existing lepers’ cemetery in the village of St Johannis, a new cemetery had to be established for the Lorenz part of the town. Close to the Spittlertor (Spital Gate), a plot of land was enclosed with a wall in 1518 and consecrated as a cemetery a year later. The family of Patrician Konrad Imhoff (1463-1519) donated funds for a chapel constructed by master builder Paul Beheim. After a short construction period, the chapel was consecrated in 1521, to St Roch of Montpellier, who was only venerated as a saint in popular tradition. In the early 16th century, the veneration of St Roch of Montpellier was very popular in Italy and was brought to Germany across the Alps via the Imhoff family’s trade connections.
The cemetery was extended three times, and has been preserved in its present shape since 1589/99. In the Second World War, the western side of the chapel suffered extensive damage, and the “Hofmeisterhaus” (house master’s house) which housed the cemetery’s administration as well as the “Totengräberhaus” (gravediggers’ house) were completely destroyed by bombs. The funeral hall of 1843 also fell victim to bombs and could only be reconstructed in 1954. Burials still take place at the cemetery today.